Journal of Experimental and Clinical Toxicology

Journal of Experimental and Clinical Toxicology

Journal of Experimental and Clinical Toxicology – Aim And Scope

Open Access & Peer-Reviewed

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Aim and Scope

Comprehensive coverage of experimental and clinical toxicology research.

Defining Excellence in Toxicology Publishing

Experimental and Clinical Toxicology publishes original research, reviews, and clinical studies spanning the complete spectrum of toxicological science—from molecular mechanisms and dose-response relationships to clinical management and regulatory applications.

Editorial Focus

Our journal seeks to publish research that advances understanding of toxic substance effects on biological systems while maintaining relevance for regulatory scientists and clinical practitioners. We emphasize translational research bridging laboratory discoveries with regulatory applications, clinical toxicology practice, and public health protection.

Experimental and Clinical Toxicology serves as a vital platform for disseminating cutting-edge findings in the field, encompassing a wide range of toxicological studies and providing valuable insights into the mechanisms, effects, and management of toxic substances across environmental, occupational, pharmaceutical, and clinical contexts.

Priority Research Areas

Mechanistic Toxicology

  • Molecular and cellular mechanisms of toxicity
  • Receptor-mediated toxic effects
  • Metabolic activation and detoxification
  • Oxidative stress and cell death pathways
  • Toxicokinetics/toxicodynamics and exposure modeling

Environmental Toxicology

  • Emerging environmental contaminants
  • Nanomaterial and microplastic toxicity
  • Heavy metals and industrial chemicals
  • Pesticides and agrochemicals
  • Ecotoxicology and environmental fate

Food & Natural Toxins

  • Food toxicology and food safety
  • Natural toxins and plant alkaloids
  • Mycotoxins and fungal contamination
  • Envenomation and animal venoms
  • Marine biotoxins and seafood safety

Pharmaceutical Safety

  • Drug safety and adverse reactions
  • Preclinical safety assessment
  • Drug-drug interactions
  • Toxicity prediction methodologies
  • Pharmacovigilance studies

Clinical Toxicology

  • Poisoning diagnosis and management
  • Antidote development and efficacy
  • Overdose treatment protocols
  • Therapeutic drug monitoring
  • Substance abuse toxicology

Regulatory & Methods

  • Alternative testing approaches (3Rs)
  • In vitro and in silico toxicology
  • Risk assessment methodologies
  • Biomarker discovery and validation
  • Adverse outcome pathways

Emerging Topics: We actively seek research on computational toxicology, QSAR modeling, high-throughput screening, organ-on-chip technologies, exposure science advances, and precision toxicology approaches that advance predictive capabilities.

Article Types

Original Research

Novel findings from experimental or clinical toxicology investigations with rigorous methodology and clear interpretation.

Reviews

Systematic reviews, meta-analyses, and authoritative narrative reviews synthesizing current evidence.

Methods Papers

Novel methodological approaches for toxicity testing, biomarker detection, or analytical procedures.

Case Reports

Detailed clinical toxicology cases with educational value and unusual presentations.

Translational Impact

We particularly encourage submissions with clear translational relevance, connecting basic toxicology research with regulatory applications, clinical practice, or public health policy. Research informing risk assessment methodologies, safety evaluation standards, and exposure guidelines provides immediate value for protecting human health.

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